Computational Core

computational-core describes software projects authored by John J. Lee and collaborators for the Computational Core of the Neuroimaging Laboratories at Washington University in St. Louis. These projects support research programs of the organizational units aforementioned.

While the scope of projects is diverse, research themes most commonly involve:

  • biophysical models of brain metabolism and function

  • instrumentation and data specific for positron emission tomography

  • instrumentation and data specific for resting-state functional magnetic resonance imaging

  • instrumentation and data specific for intracranial electroencephalography

  • data archives based on XNAT

  • standardized data formats such as 4dfp, NIfTI, CIFTI, and BIDS

  • inferential methodologies drawn from Bayesian statistics, expectation maximization, Markov chain Monte Carlo, graphical models, and deep learning

  • reuse of mature pre-existing projects such as FSL, FreeSurfer, Tensorflow, Pytorch, and MONAI.

This project is under active development.

Contents

  1. package mlfourd

    • transparently supports 4dfp, NIfTI, CIFTI, FreeSurfer, iEEG and BIDS data formats

    • provides adapter patterns implementing client interfaces familiar for neuroscience tasks

    • uses state patterns instantiating lightweight objects optimized for categories of data and behavior

  2. package mlraichle

    • provides biophysical models for oxygen and glucose metabolism

    • provides image-derived input functions

    • supports instrumentation related to the Siemens Biograph mMR

  3. package mlvg

    • supports instrumentation related to the Siemens Biograph Vision

  4. package mlarbelaez

    • supports instrumentation related to the Siemens ECAT EXACT HR+

  5. project cc-graph-nets

    • implements Deep Minds’ Graph Nets library for neuroimaging

  6. project cc-trax

    • implements Google Brain’s Trax and transformers for neuroimaging

  7. project cc-vision-transformer

    • implements vision transformers and MLP-mixer architectures for neuroimaging

Feature highlights

API Reference

Indices and tables